Experience with production and control of attenuated poliovirus (Subinstrains) in human diploid cells

experience with production and control of attenuated poliovirus (sabinstrains) in human diploid cells

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Improvement in the yield of oral poliovirus vaccine (Sabin strains) produced in human diploid cells

Evaluation of Live Attenuated Measles Vaccines Prepared in Human Diploid Cells for Reimmunization

improvement in the yield of oral poliovirus vaccine (sabin strains) produced in human diploid cells

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Efficacy of oral poliovaccine made in human diploid cells

Improvement in the yield of oral poliovirus vaccine (Sabin strains) produced in human diploid cells.

When stationary cultures of human diploid cells in conventional Roux bottles were replaced by the development of cells in roller bottles, the yield of poliovirus, Sabin strains type 1 and 2, showed an increase of 0.5 to 1 log10. No significant difference was noticed in the yield of these viruses cultured in WI-38 and MRC-5 human diploid cells.